Collie, Sheltie... - defeito genético - defeito de MDR1

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Finwe
Mensagens: 4
Registado: domingo abr 01, 2007 6:44 pm

domingo abr 01, 2007 7:08 pm

Bem – vindo em www.mdr1-defekt.de

Please excuse me writing in English, but unfortunately I do not speak Portuguese.

But I have important informations for all owners and friends of the Collie and related breeds.

Collies react more sensitively to certain medical substances like Ivermectin. This was already detected by breeders years ago - some of their dogs died. They talked about "the ivermectin-sensitive Collie" and they were concerned about this and asked their vets.
So in several countries, research was conducted.

In 2001 in the USA, the reason for this sensitivity was discovered:
This reason is a serious gene defect within the so called "MDR1 gene".
"MDR" means "multi drug resistance" - and due to the defect about 30% of all Collies don´t have this resistance.
So not only Ivermectin but many other medical substances can cause unwelcome side effects - some of them fatal.
And the lists showing this medical substances are still growing.

There is a test to see whether a dog is affected by the defect or not.

You can search the web for more informations and you can look here:
1. http://www.vetmed.wsu.edu/depts-VCPL/#Drugs (in English)
2. http://www.mdr1-defekt.de/index.php?lang=PT (in English and German and Portuguese)

I hope that this will be of some interest for you.

Please excuse the disturbance - and ask, if you have more questions!

With greetings from Germany,
Kris
leonildecarvalho
Membro Veterano
Mensagens: 19895
Registado: segunda dez 16, 2002 1:46 am
Localização: Abul-Fadl Nadr al-Hamdani

domingo abr 01, 2007 7:30 pm

Thanks for the information but this post should be in the Dogs section of the animal's forum.

:arrow: http://animais2.clix.pt/forum/viewforum.php?f=2

Leo

ps- this section is only for cats :wink:
<p>Desejo a mesma sorte, que a triste sorte dos animais que nao sejam ajudados por quem nao deixa que se os ajude. Autor desconhecido</p>
<p>&nbsp;</p>
<p>-------------------------------------------------------------</p>
<p>Regurgito nas postas de pescada dos arrotadores. Autor desconhecido</p>
<p>&nbsp;</p>
<p>&nbsp;</p>
Finwe
Mensagens: 4
Registado: domingo abr 01, 2007 6:44 pm

domingo abr 01, 2007 7:51 pm

Cats? How nice! I love cats!
:lol:

Thank you for the information. Perhaps I should learn some portuguese?

Kris
leonildecarvalho
Membro Veterano
Mensagens: 19895
Registado: segunda dez 16, 2002 1:46 am
Localização: Abul-Fadl Nadr al-Hamdani

domingo abr 01, 2007 10:55 pm

Finwe Escreveu:Cats? How nice! I love cats!
:lol:

Thank you for the information. Perhaps I should learn some portuguese?

Kris
Why not? Here you can try to start... :wink: :D
Just an idea :wink: :idea:

Leo
<p>Desejo a mesma sorte, que a triste sorte dos animais que nao sejam ajudados por quem nao deixa que se os ajude. Autor desconhecido</p>
<p>&nbsp;</p>
<p>-------------------------------------------------------------</p>
<p>Regurgito nas postas de pescada dos arrotadores. Autor desconhecido</p>
<p>&nbsp;</p>
<p>&nbsp;</p>
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